1. Background
Although modern medicine continues to make steady progress, many health challenges remain, including rare diseases, age-related diseases, and physical injury. Regenerative medicine, particularly therapies using iPS cells, holds the potential to address these challenges. Since iPS cells can be generated from a patient’s or healthy own cells, and have the ability to differentiate into various cells. However, cell-adhesive coating materials are essential for iPS cell culture, and conventional protein-derived coating materials have faced issues in terms of uniformity and stability, becoming a major barrier to the industrial expansion and practical application of regenerative medicine. Ceglu™ is a new polymer product developed to address these challenges, and from the outset, SEKISUI CHEMICAL has been advancing its business development with global expansion in mind.
2. Expansion in North America
North America is one of the regions where research and development in regenerative medicine, drug development, and cell therapy are thriving and represents the world’s largest cell culture market. By enabling a wide range of researchers and companies in this region to use Ceglu™ cultureware, SEKISUI CHEMICAL aims to help accelerate the practical application of regenerative medicine. SEKISUI CHEMICAL has established a marketing base in San Diego, California, and has been actively engaged in activities aimed at expanding into North America. By providing samples to cell manufacturing institutions and university researchers, strong demand for Ceglu™ has been confirmed. Through the sales of this product, SEKISUI CHEMICAL will contribute to the further development of regenerative medicine in North America.
- (Sales area)
United States, Canada
(Product lineup)
Ceglu™ cultureware
・Ceglu™ multiwell plate (6-well)
・Ceglu™ multiwell plate (96-well)
・Ceglu™ dish (100mm) 
Ceglu™cultureware
3. About Ceglu™
Ceglu™ is a chemically synthesized polymer that enables the culture of iPS cells and can be solubilized to coat the surfaces of various materials. Compared to proteins, it has high stability at room temperature and does not require a cold chain.* In addition, it does not contain any animal-derived ingredients in its production process and offers high safety.
SEKISUI CHEMICAL provides Ceglu™ coating solution, a coating agent, and Ceglu™ cultureware, pre-coated plates, and aims to establish a consistent cell-adhesion platform from laboratory scale to manufacturing scale. Examples of its application to date include differentiation into iPS cell-derived cardiomyocytes, improved reproducibility of cell quality through combination with automated culture equipment, and scale-up of cell culture through coating of nonwoven fabrics and microcarriers.
Ceglu™ Website: https://www.sekisui-cell.jp/en/products/ceglu/
*Cold chain: A logistics method that keeps fresh food, pharmaceuticals, etc. at low temperatures without interruption throughout the production, transportation, and consumption process.
4. Future outlook
Sales launches in Europe and Asia are also scheduled sequentially, and SEKISUI CHEMICAL will accelerate the global expansion of the Ceglu™ cell-adhesion platform and help accelerate the practical application of regenerative medicine.
About SEKISUI CHEMICAL Group
Headquartered in Japan, SEKISUI CHEMICAL CO., LTD. (TSE: 4204) and its subsidiaries make up the SEKISUI CHEMICAL Group. 26,000 employees in over 155 companies throughout 20 countries and regions aim to contribute to improving the lives of the people of the world and the earth’s environment. Thanks to a history of innovation, dedication and a pioneering spirit, SEKISUI CHEMICAL now holds leading positions in its three diverse business divisions as well as top global market share in interlayer film, foam products, conductive particles and more.
For inquiries
SEKISUI CHEMICAL CO., LTD.
Public Relations Group, Corporate Communication Department
Email: kouhou@sekisui.com
Inquiries related to sales and technologies
SEKISUI DIAGNOSTICS LLC
SEKISUI CHEMICAL CO., LTD.
Life Science Business Development Division
E-mail: support_life@sekisui.com
Disclaimer
This press release may contain forward-looking statements. Such forward-looking statements are based on current expectations and beliefs and are subject to a number of factors and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements due to changes in global economic, business, competitive market and regulatory factors.
